Nitric oxide as a secretory product of mammalian cells.
نویسنده
چکیده
Evolution has resorted to nitric oxide (NO), a tiny, reactive radical gas, to mediate both servoregulatory and cytotoxic functions. This article reviews how different forms of nitric oxide synthase help confer specificity and diversity on the effects of this remarkable signaling molecule.
منابع مشابه
P-95: Effect of Nano Silver on Nitric Oxide Production in Chicken's Sertoli Cells
Background: Chicken sertoli cells are a model to evaluate the effects of toxic Materialss. These cells can actively proliferate in the in vitro conditions and they are able to passage several times. Because of the widespread use of nanosilver in life and also few studies on the effects of these Materialss on different cell lines, evaluation of its toxic effects is felt. Mechanism of nanosilver ...
متن کاملP-113: Survey of In Vitro Effect of Resveratrol on Nitric Oxide Secretion of Human Endometrial Epithelial Cells
Background: Resveratrol is a natural polyphe- nolic compound, synthesized by plants as a phytoalexin and protects against ultraviolet radiation and fungal infection. Nitric oxide is formed from L-arginine through nitric oxide synthases (NOS), a group of enzymes that structurally resemble cytochrome P-450 reductase. In females, circulating NO is increased during follicle development and decrease...
متن کاملAloe vera toxic effects: expression of inducible nitric oxide synthase (iNOS) in testis of Wistar rat
Objective(s): Nitric oxide (NO), a product of inducible nitric oxide synthase (iNOS), contributes in germ cell apoptosis. This study was aimed to evaluate the effects of Aloe vera gel (AVG) on male Wistar rat reproductive organ, serum NO level, and expression of iNOS gene in leydig cells. Materials and Methods:Adult male Wistar rats (n=36) were used for experiments in three groups. The experim...
متن کاملAGE proteins as a causative factor in Alzheimer's Disease
The reaction between reducing sugars and protein free amines, known as the Maillar reaction results in the formation of advanced glycation endproducts (AGEs). AGE modification changes the structure of proteins to amyloid cross-beta structure. These protein structures can activate receptors known as RAGE on glial cells (microglia and astrocytes), and induce the expression of inducible nitric oxi...
متن کاملNitric Oxide Production and Apoptosis Induction in T Cells through Stimulation of Mesenchymal Stem Cells with Zymosan
Background & Aims: Mesenchymal stem cells (MSCs) are non-hematopoietic multipotant cells, which multiply through attaching to culture plates. Toll-like receptors (TLRs) are inherent immune sensors and regulators of immunomodulatory activities of MSCs. The aim of this study was to investigate the effects of zymosan on stem cell polarization into anti-inflammatory phenotypes through the productio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology
دوره 6 12 شماره
صفحات -
تاریخ انتشار 1992